Know what Sildenafil is used for, how to take it, and which side effects to expect when starting it. Sildenafil is used to treat erectile dysfunction in adult men or pulmonary arterial hypertension in adults and children, depending on the brand or formulation. Includes sildenafil side effects, interactions, and indications. Evidence-based academic analysis of sildenafil citrate: mechanism, pharmacokinetics, clinical efficacy, and safety profile. VIAGRA (sildenafil citrate), an oral therapy for erectile dysfunction, is the citrate salt of sildenafil, a selective inhibitor of cyclic guanosine monophosphate (cGMP)-specific. Viagra is a prescription medicine used to treat the symptoms of erectile dysfunction. Learning about dosages, side effects, drug interactions, warnings, and more. Sildenafil works by blocking an enzyme in the body called PDE5, which helps relax certain blood vessels. For erectile dysfunction, it increases blood flow to the penis when aroused. To ensure you’re getting the best results from sildenafil, you should make sure that you’re using it correctly and safely. Below we have detailed the answers to some of the most commonly asked questions about taking sildenafil correctly. For most patients, the recommended dose is 50 mg taken, as needed, approximately 1 hour before sexual activity. However, sildenafil citrate tablets may be taken anywhere from 30 minutes to 4 hours before sexual activity (2.1) Sildenafil tablets, USP, an oral therapy for erectile dysfunction, is the citrate salt of sildenafil, a selective inhibitor of cyclic guanosine monophosphate (cGMP)-specific phosphodiesterase type 5 (PDE5). Sildenafil is used to treat erectile dysfunction (also called sexual impotence). Sildenafil belongs to a group of medicines called phosphodiesterase 5 (PDE5) inhibitors.