Find patient medical information for Vybrique (Sildenafil) on WebMD including its uses, side effects and safety, interactions, pictures, warnings, and user ratings Sildenafil works by blocking an enzyme in the body called PDE5, which helps relax certain blood vessels. For erectile dysfunction, it increases blood flow to the penis when aroused. Sildenafil (Viagra) is a tablet that's taken by mouth for erectile dysfunction (ED) in adults. It works as a phosphodiesterase-5 (PDE5) inhibitor to help people get an erection or keep an erection that lasts for sex. Sildenafil is in a class of medications called phosphodiesterase (PDE) inhibitors. Sildenafil treats erectile dysfunction by increasing blood flow to the penis during sexual stimulation. Sildenafil oral tablet is a prescription medication used to treat erectile dysfunction (ED) and pulmonary arterial hypertension (PAH). Sildenafil is used to treat erectile dysfunction in adult men or pulmonary arterial hypertension in adults and children, depending on the brand or formulation. Includes sildenafil side effects, interactions, and indications. Sildenafil, sold under the brand name Viagra among others, is a medication used to treat erectile dysfunction and pulmonary arterial hypertension. [4][8] It is also sometimes used off-label for the treatment of certain symptoms in secondary Raynaud's phenomenon. [9] NHS medicines information on dosage for sildenafil, how to take it and what to do if you miss a dose or take too much. Viagra (sildenafil) is used to treat erectile dysfunction or impotence in men. Includes Viagra side effects, interactions and indications. Sildenafil is used to treat erectile dysfunction (also called sexual impotence). Sildenafil belongs to a group of medicines called phosphodiesterase 5 (PDE5) inhibitors.