Topamax (topiramate) is used to prevent seizures in adults and children and to prevent migraine headaches. Learn about side effects, interactions and indications. Learn about side effects, uses, dosage, and more for Topamax (topiramate). It’s a prescription drug for migraine and epilepsy in children and adults. Topamax (topiramate) is a prescription tablet or capsule used to prevent migraine and treat epilepsy. Learn about its side effects, uses, dosage, and more. Topiramate, marketed as Topamax among other names, is an oral medication primarily prescribed for the treatment of epilepsy and the prophylaxis of migraines. [8] Eligible patients using commercial or private insurance can save on out-of-pocket costs for TOPAMAX ® (topiramate). Eligible patients pay $4 per fill. There is a $150 limit for each 30-day supply. There is a maximum program benefit of $1,800 or 12 fills per calendar year, whichever comes first. Concomitant administration of phenytoin or carbamazepine with TOPAMAX® resulted in a clinically significant decrease in plasma concentrations of topiramate when compared to TOPAMAX® given alone. The Topamax® sprinkle capsule or Qudexy® XR extended-release capsule may be swallowed whole or opened and sprinkled on a small amount (1 teaspoon) of soft food (eg, applesauce). Find patient medical information for Topiramate (Topamax) on WebMD including its uses, side effects and safety, interactions, pictures, warnings, and user ratings TOPAMAX is indicated as initial monotherapy for the treatment of partial-onset or primary generalized tonic-clonic seizures in patients 2 years of age and older. Topamax (topiramate) is an anticonvulsant medication used to treat epilepsy and migraine headaches. 1 It's also used off-label to treat a wide range of mood and eating disorders and to aid in substance abuse therapy.