Cartagena spreads across Colombia's Caribbean coast. Except for their airplanes landing in the north, a majority of travelers' time is spent in the eastern area of the city. This coastal portion. Plaza Santo Domingo is ranked 3 out of 12 things to do in Cartagena. See pictures and our review of Plaza Santo Domingo. Sanctuary of Saint Peter Claver is ranked 5 out of 12 things to do in Cartagena. See pictures and our review of Sanctuary of Saint Peter Claver. Playa Blanca is ranked 7 out of 12 things to do in Cartagena. See pictures and our review of Playa Blanca. The best way to get around Cartagena is by taxi. Taxis make it easy to get between distinct points in the city, including Cartagena's Rafael Núñez International Airport (CTG), while short jaunts. From Miami, Oceania Vista calls at George Town, Cayman Islands; Cartagena, Colombia; Puerto Quetzal, Guatemala; Acapulco and Manzanillo, Mexico; and San Diego before ending in Los Angeles. Guide to the best hotels and things to do in Cartagena. Maps, travel tips and more. Ranking of the top 12 things to do in Cartagena. Travelers favorites include 1 Old City Walls, 2 San Felipe de Barajas Castle and more. Guide to the best hotels and things to do in Cartagena. Maps, travel tips and more. Guide to the best hotels and things to do in Cartagena. Maps, travel tips and more.