Medscape - Indication-specific dosing for Tylenol with Codeine, Tylenol 3, Tylenol 4 (codeine, acetaminophen), frequency-based adverse effects, comprehensive interactions. Tylenol 3 is prescribed to treat moderate pain and reduce persistent cough. It's commonly used after surgery, for dental pain, or for cough from conditions like bronchitis. Acetaminophen is used to relieve pain and reduce fever in patients. It does not become habit-forming when taken for a long time. But acetaminophen may cause other unwanted effects when taken in large doses, including serious liver damage. Overview: Acetaminophen/codeine is used to treat certain types of pain. It reduces pain signals and changes how your body feels pain. Common side effects include constipation and feeling sleepy or. Tylenol 3 is a prescription painkiller that combines acetaminophen with codeine. Learn its side effects, dosages, and risk of addiction and dependence. What is Tylenol with Codeine 3? Tylenol with Codeine 3 is a combination medicine used to relieve moderate to severe pain. Tylenol with Codeine 3 may also be used for purposes not listed in this medication guide. Tylenol number 3 is an effective, short-term option for managing pain. Explore its uses and side effects, as well as how the medication compares to Vicodin here.