Read on for Tylenol PM dosage information, including typical dosage and what to do if you take too much. Tylenol PM combines a proven pain reliever and sleep aid to help you fall asleep faster and stay asleep through the night. Effective, non-habit forming relief. Tylenol PM is a combination medicine used to treat occasional insomnia associated with minor aches and pains. Tylenol PM is not for use in treating sleeplessness without pain, or sleep problems that occur often. Buy Tylenol PM Extra Strength Nighttime Pain Relief and Sleep Aid Caplets, Fast, Strong, 150 Count at Walmart.com. HSA/FSA eligible, making your health and wellness purchases more manageable TYLENOL® PM is specifically formulated for minor aches and pains with accompanying sleeplessness. Its combination of acetaminophen and a nighttime sleep aid relieves minor pain and helps you fall asleep. Learn about Tylenol PM Extra Strength (acetaminophen / diphenhydramine) usage and dosing. Read the latest news and reviews about the drug as well as potential side effects and popular alternatives. Here’s a closer look at Tylenol PM, its recommended use, and potential side effects. Tylenol PM is a popular over-the-counter medication that combines two active ingredients: acetaminophen and diphenhydramine. It is primarily used as a pain reliever and fever reducer, but it also helps with sleeplessness and occasional insomnia. Tylenol PM contains two active ingredients: 500 mg of acetaminophen (a pain reliever) and 25 mg of diphenhydramine hydrochloride (an antihistamine that causes drowsiness). The combination is designed to relieve minor aches and pains while helping you fall asleep. Tylenol PM can be used by adults and children 12 years and older. This product is an over-the-counter medication, and is also FSA/HSA eligible; check your plan for details as plans may vary. With this 100-count bottle of Tylenol PM caplets pain reliever plus sleep aid, we give you a better night.