What is vardenafil? Vardenafil is used in adult men to treat erectile dysfunction (impotence). Vardenafil may also be used for purposes not listed in this medication guide. Vardenafil belongs to a group of medicines, known as phosphodiesterase-5 (PDE-5) inhibitors, which are used to treat erectile dysfunction or pulmonary arterial hypertension. What is this medication? VARDENAFIL (var DEN a fil) treats erectile dysfunction (ED). It works by increasing blood flow to the penis, which helps to maintain an erection. Vardenafil, sold under the brand name Levitra among others, is a medication that is used for treating erectile dysfunction. [1][2] It is a PDE5 inhibitor. [1] It is taken by mouth. Vardenafil is a PDE5 inhibitor used to treat erectile dysfunction in adult men. Uses, dosing, side effects and interactions, explained by a pharmacist. Vardenafil is in a class of medications called phosphodiesterase (PDE) inhibitors. It works by increasing blood flow to the penis during sexual stimulation. This increased blood flow can cause an erection. Vardenafil does not cure erectile dysfunction or increase sexual desire. Description Vardenafil is used to treat men with erectile dysfunction (sexual impotence). It belongs to a group of medicines called phosphodiesterase 5 (PDE5) inhibitors. These medicines prevent an enzyme called phosphodiesterase type-5 from working too quickly. The penis is one of the areas where this enzyme works. Levitra (vardenafil hydrochloride) is an erectile dysfunction agent that works by blocking a certain enzyme (phosphodiesterase-PDE5) used to treat erectile dysfunction (impotence). Vardenafil is a first-choice medication for erectile dysfunction (ED). It's no longer sold under the brand name Levitra, but it's available as generic tablets and orally disintegrating tablets (ODTs). Common side effects of vardenafil include headache, flushing, and stuffy nose. Vardenafil is FDA approved to treat erectile dysfunction (ED). It works by allowing more blood to flow to your penis and making it easier to achieve an erection. Generic vardenafil is equally.