The 1 doctor recommended OTC topical pain relief brand, Voltaren is approved for arthritis pain. It has a triple effect that relieves arthritis pain, improves mobility and reduces stiffness to provide prescription-strength relief over the counter and keep you in control. Voltaren gel contains diclofenac, a nonsteroidal anti-inflammatory drug (NSAID). Diclofenac works by reducing substances in the body that cause pain and inflammation. Voltaren oral tablets are used to treat mild to moderate pain, or signs and symptoms of osteoarthritis or rheumatoid arthritis. Voltaren is also used to treat ankylosing spondylitis. Topical diclofenac (Voltaren) is commonly used to treat arthritis pain in the hands, wrists, elbows, feet, ankles, or knees. Learn more about Voltaren gel for arthritis. Voltaren Arthritis Pain Gel is a powerful medicated gel that directly targets and treats arthritis at the site of pain. It has a triple effect of relieving arthritis pain, improving mobility, and reducing stiffness to help you move more freely. Voltaren is a medicated gel that you can apply to the skin for relief from muscle and joint pain. It may take multiple days of application for significant pain relief. Voltaren (diclofenac) is used to treat symptoms of pain associated with rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, dysmenorrhea, and mild-to-moderate pain.