DESCRIPTION ZYBAN (bupropion hydrochloride) Sustained-Release Tablets are a non-nicotine aid to smoking cessation. ZYBAN is chemically unrelated to nicotine or other agents currently used in. The risks of ZYBAN should be weighed against the benefits of its use. ZYBAN has been demonstrated to increase the likelihood of abstinence from smoking for as long as 6 months compared to. Zyban is a nicotine-free quit aid available by prescription-only. Learn how it can help reduce your urge to smoke, as well as usage information and side effects. Find patient medical information for Bupropion (Wellbutrin, Zyban, and others) on WebMD including its uses, side effects and safety, interactions, pictures, warnings, and user ratings Bupropion extended-release (SR), brand name Zyban, is an atypical antidepressant. It's taken by adults for smoking cessation (quitting smoking) only. It works by easing symptoms of nicotine withdrawal and lowering your cravings for nicotine. Wellbutrin SR and XL are available in generic form in the United States and Canada. In 1997, bupropion was approved by the FDA for use as a smoking cessation aid under the name Zyban. [198][196] In 2006, Wellbutrin XL was similarly approved as a treatment for seasonal affective disorder. [199][200] Zyban is a brand of bupropion, which is a medication that helps you quit smoking. It works by reducing cravings for nicotine. Detailed dosage guidelines and administration information for Zyban (bupropion hydrochloride). Includes dose adjustments, warnings and precautions. Zyban (Bupropion Hcl) may treat, side effects, dosage, drug interactions, warnings, patient labeling, reviews, and related medications including drug comparison and health resources. Zyban helps people stop smoking by reducing cravings and other withdrawal effects. Learn about side effects, interactions and indications.