Amiodarone is used to treat certain types of serious irregular heartbeat. Learn about side effects, drug interactions, dosages, warnings, and more. Learn about the side effects of amiodarone, from common to rare, for consumers and healthcare professionals. Amiodarone is a medication that prevents and treats an irregular heartbeat (arrhythmia). It works by stabilizing your heart’s rhythm. This color will usually fade after treatment with amiodarone has ended, although it may take several months. Check with your doctor if this color change occurs. Grapefruit and grapefruit juice may increase the side effects of amiodarone by increasing the amount of this medicine in your body. Amiodarone is a medication used to treat irregular heart rhythms, or arrhythmias, belonging to the class III group of antiarrhythmic drugs, also known as potassium channel blockers. Amiodarone can be given orally or by injection to prevent or manage serious medical conditions such as cardiac arrest and arrhythmias. As amiodarone reduces the excitability of cardiac cells, it is considered quite. Amiodarone (Cordarone) is an antiarrhythmic medication used to treat ventricular tachycardia or ventricular fibrillation. Includes amiodarone side effects, interactions and indications. Amiodarone is an antiarrhythmic medication used to treat and prevent a number of types of cardiac dysrhythmias. [4] This includes ventricular tachycardia, ventricular fibrillation, and wide complex tachycardia, atrial fibrillation, and paroxysmal supraventricular tachycardia. [4] Evidence of benefit for cardiac arrest is poor. [5] It can be given by mouth, intravenously, or intraosseously. [4. Amiodarone: learn about side effects, dosage, special precautions, and more on MedlinePlus Find patient medical information for Amiodarone on WebMD including its uses, side effects and safety, interactions, pictures, warnings, and user ratings Amiodarone is a frequently prescribed anti-arrhythmic medication. Amiodarone is approved by the U.S. Food and Drug Administration (FDA) specifically for the treatment of life-threatening ventricular arrhythmias. However, this drug is also widely used off-label to treat supraventricular tachyarrhythmias, such as atrial fibrillation, and to prevent ventricular tachyarrhythmias in high-risk.