Learn about the side effects of amitriptyline, from common to rare, for consumers and healthcare professionals. Amitriptyline hydrochloride, USP, a dibenzocycloheptadiene derivative, is a white, or practically white, odorless, crystalline compound which is freely soluble in water and alcohol. Amitriptyline Tablets Amitriptyline is a medication that treats depression. It works by increasing the amount of serotonin and norepinephrine in your brain. These hormones help regulate your mood. Brand names for this medication include Elavil® and Vanatrip®. Amitriptyline is indicated for the treatment of major depressive disorder, neuropathic pain, and for the prevention of migraine and chronic tension headache. It can be used for the treatment of nocturnal enuresis in children older than 6 after other treatments have failed. [11] Amitriptyline is a prescription medication used to treat mental/mood problems such as Depression. Amitriptyline is available under the following different brand names: Elavil, Levate Find patient medical information for Amitriptyline (Amitid, Elavil, Endep) on WebMD including its uses, side effects and safety, interactions, pictures, warnings, and user ratings View amitriptyline hydrochloride information, including dose, uses, side-effects, pregnancy, breast feeding and contra-indications. Amitriptyline may cause some people to be agitated, irritable, or display other abnormal behaviors. It may also cause some people to have suicidal thoughts and tendencies or to become more depressed. If you or your caregiver notice any of these adverse effects, tell your doctor right away. Amitriptyline is a tricyclic antidepressant used to treat depression and, off-label, conditions like insomnia, anxiety, migraines, and chronic pain. Amitriptyline belongs to an older class of antidepressants called tricyclic antidepressants, or TCAs. It works by blocking the reabsorption of two chemical messengers in the brain: serotonin and norepinephrine.