Domperidone is a prescription medicine that helps reduce nausea and vomiting by improving stomach and intestinal motility. It is commonly used for symptoms linked to delayed gastric emptying, such as indigestion, bloating, and gastroesophageal reflux disease (GERD). Find out how domperidone treats feeling sick (nausea) and vomiting, and how to take it. NHS medicines information on domperidone – what it's used for, side effects, dosage and who can take it. Domperidone is a medicine that increases the movements or contractions of the stomach and bowel. Domperidone is also used to treat nausea and vomiting caused by other drugs used to treat Parkinson's Disease. Domperidone is to be given only by or under the immediate supervision of your doctor. Domperidone is a drug that has been prescribed to increase breast milk supply. Learn more about it, if it works, and if it's safe to use. Q. Can I take Domperidone for morning sickness? Domperidone is not indicated or recommended for treating morning sickness. Please consult your doctor if you plan to take any medicine for treating morning sickness. Domperidone is an anti-sickness medicine. It helps you to stop feeling or being sick (nausea or vomiting). It works by causing the muscles at the top of your stomach to tighten and the muscles at the bottom of your stomach to relax. This makes you less likely to be sick (vomit). View domperidone information, including dose, uses, side-effects, renal impairment, pregnancy, breast feeding, contra-indications and important safety information. 1.1Nausea and vomiting. 1.2Gastroparesis. 1.3Lactation. 1.4Other uses. 1.4.1Parkinson's disease. 1.4.2Other gastrointestinal uses. 1.5Available forms. 2Veterinary uses. Domperidone is not an FDA-approved drug for any indication, or use, in humans. Domperidone is approved in some countries, but not in the U.S., to treat certain gastrointestinal disorders. It is used to treat stomach-related issues, such as nausea and vomiting, as well as stomach pain and discomfort caused by decreased movement of the stomach and upper gastrointestinal (GI) tract. It is also used to boost breastmilk supply. Domperidone works by blocking dopamine receptors in the gut.