The FDA is taking decisive steps to help strengthen U.S. pharmaceutical manufacturing, improve supply chain resilience, and ensure Americans have reliable access to safe, effective, high-quality. FDA Industry Systems (FIS) was created to facilitate making submissions to the U.S. Food and Drug Administration (FDA), including registrations, listings, and other notifications. The Food and Drug Administration is responsible for protecting the public health by ensuring the safety, efficacy, and security of human and veterinary drugs. The FDA is responsible for protecting the public health by ensuring the safety, efficacy, and security of human and veterinary drugs, biological products, and medical devices; and by ensuring the. The Food and Drug Administration (FDA) is responsible for protecting the public health by assuring the safety, efficacy, and security of human and veterinary drugs, biological products, medical devices, our nation's food supply, cosmetics, and products that emit radiation. The Food and Drug Administration (FDA) is a federal agency of the United States Department of Health and Human Services (HHS). Contact Us Food and Drug Administration Food and Drug Administration White Oak Campus 10903 New Hampshire Ave Silver Spring, MD 20993 United States Primary 1-888-INFO-FDA 1-888-463-6332.