Hydrocodone Bitartrate prescription and dosage information for physicians and health care professionals. Pharmacology, adverse reactions, warnings, and Hydrocodone Bitartrateside effects. Hydrocodone bitartrate ER first gained FDA approval on October 25, 2013, under the brand name Zohydro ER. It is a Schedule II controlled substance, meaning it has an accepted medical use but a high potential for misuse, abuse, and dependence. There is a greater risk of overdose and death with extended-release opioid formulations, including hydrocodone bitartrate. This drug should be used only when other treatments have failed to provide relief. Hydrocodone is an opioid that binds to specific receptors in your body to give you pain relief. Common side effects may include constipation, dizziness, drowsiness, headache, and stomach pain. Hydrocodone bitartrate is a potent opioid analgesic frequently prescribed for the management of moderate to severe pain. Trade names for this drug include Vicodin, Lortab, and Norco, though there are numerous generic versions available as well. HYDROcodone Bitartrate (Antitussive) reference guide for safe and effective use from the American Society of Health-System Pharmacists (AHFS DI). Hydrocodone bitartrate is a phenanthrene-derivative opiate agonist that is used as an analgesic and antitussive agent.