Application to real-life: Using 4% topical lidocaine in a 5-mL nebulizer will give a total dose of 200 mg. This is within the range of safe, studied doses, and will provide the anesthetic effect you (and the patient) desires. Application to real-life: Using 5-mL of 4% topical lidocaine solution via nebulizer will provide a total dose of 200 mg. This is within the range of safe, studied doses, and may provide the anesthetic effect you (and the patient) desires. Nebulized lidocaine offers a valuable option for patients with intractable cough when standard treatment fails. Many clinicians recognize its rapid suppression of cough, often within 15 minutes, and its generally favorable safety profile. Nebulized lidocaine for cough relief. Nebulized lidocaine is often used in bronchoscopy to increase comfort of patient and allow for further visualization of the airway. Nebulized lidocaine is administered with the goal of analgesia of the upper airway, thereby limiting sedation and supplemental lidocaine doses; however, there has been insufficient evidence in the literature to support this claim. This resource explains how to use lidocaine in your nebulizer machine to help relieve your cough. This resource explains how to use lidocaine (LY-doh-kane) in your nebulizer machine to help relieve your cough. Lidocaine is a local anesthetic (medicine that numbs an area of your body). Nebulized lidocaine may be an important treatment option for adults with difficult-to-control chronic cough. The data from our study should help health-care providers inform patients about likelihood of success, treatment burden, and risk of adverse effects. Nebulized lidocaine (also called lignocaine) is primarily used in palliative care to relieve intractable cough in terminal illness, though it has additional applications in bronchoscopy and investigational uses for asthma. 1 This page includes the following topics and synonyms: Nebulized Lidocaine.