The meaning of LOSS is destruction, ruin. How to use loss in a sentence. LOSS definition: 1. the fact that you no longer have something or have less of something: 2. a disadvantage caused…. Learn more. Many English learners confuse lose, loss, and lost because these words come from the same root but serve different grammatical roles. LOSS meaning: 1. the fact that you no longer have something or have less of something: 2. a disadvantage caused…. Learn more. If you no longer have something, you experience a loss, like the loss of a favorite sock. When something lessens, or gets smaller, that's also a loss, as in weight loss. Loss function, in statistics, a function representing the cost associated with an event Path loss, the attenuation undergone by an electromagnetic wave in transit from a transmitter to a receiver Free-space path loss, the loss in signal strength that would result if all influences were sufficiently removed having no effect on its propagation Loss (Ctrl+Alt+Del) Loss by Tim Buckley for the webcomic Ctrl+Alt+Del Loss , sometimes referred to as loss.jpg , [1] is a comic strip published on June 2, 2008, by Tim Buckley in his gaming-related webcomic Ctrl+Alt+Del. It is part of a storyline in which the main character Ethan and his fiancée Lilah are expecting their first child. Loss, also known as CADbortion, Loss.jpg and | || || |_, is a series of parodies based on a dramatic cartoon strip from the webcomic series Ctrl+Alt+Del in Define loss. loss synonyms, loss pronunciation, loss translation, English dictionary definition of loss. n. 1. The act or an instance of losing: nine losses during the football season. 2. a. One that is lost: wrote their flooded house off as a loss. b. LOSS definition: detriment, disadvantage, or deprivation from failure to keep, have, or get. See examples of loss used in a sentence.