Detailed Metronidazole dosage information for adults and children. Includes dosages for Bacterial Infection, Skin or Soft Tissue Infection, Skin and Structure Infection and more; plus renal, liver and dialysis adjustments. Metronidazole is used to treat certain infections in the body caused by bacteria including sexually transmitted diseases (STDs) and bacterial vaginosis (an infection caused by too much of certain types of harmful bacteria in the vagina) in women. Metronidazole is in a class of medications called nitroimidazole antimicrobials. INTRODUCTION Metronidazole is one of the mainstay drugs for the treatment of anaerobic infections [1,2]. It is approved by the US Food and Drug Administration (FDA) for the treatment of anaerobic and protozoal infections. Metronidazole exerts its antimicrobial effects through the production of free radicals that are toxic to the microbe. MECHANISM OF ACTION Activity against most obligate. Metronidazole is a nitroimidazole antimicrobial that kills anaerobic bacteria and parasites via DNA-damaging free radicals. It treats trichomoniasis, amebiasis, and serious anaerobic infections, and prevents post-colorectal-surgery infection. Learn about side effects, interactions, and indications. Metronidazole is used to treat bacterial infections in different areas of the body. It is also used to treat infections caused by protozoa (eg, trichomoniasis and amebiasis) and infections caused by bacteria that do not need oxygen to survive. The extended-release tablets are used to treat women with vaginal infections (bacterial vaginosis). Metronidazole is a prescription antibiotic medication prescribed for the treatment of a variety of parasitic and bacterial infections of the vagina, gynecological area, skin, intra-abdominal cavity, blood, bone, joint, nervous system, and heart. Metronidazole is used orally or IV as adjunctive therapy to treat bone and joint infections caused by Bacteroides species, including the B. fragilis group, in adults. [97][152][197][495] Guidelines from the IDSA published in 2015 on treatment of native vertebral osteomyelitis in adults list metronidazole as one of several oral antibacterial. Find patient medical information for Metronidazole (Flagyl, Likmez) on WebMD including its uses, side effects and safety, interactions, pictures, warnings, and user ratings Metronidazole is used to treat a certain type of vaginal infection (bacterial vaginosis) in women who are not pregnant. Learn about side effects, drug interactions, dosages, warnings, and more. Metronidazole, sold under the brand name Flagyl and Metrogyl among others, is an antibiotic and antiprotozoal medication. [10] It is used either alone or with other antibiotics to treat pelvic inflammatory disease, endocarditis, and bacterial vaginosis. [10] It is effective for dracunculiasis, giardiasis, trichomoniasis, and amebiasis. [10] It is an option for a first episode of mild-to.