It is used to treat gastric and duodenal ulcers, erosive esophagitis, and gastroesophageal reflux disease (GERD). GERD is a condition where the acid in the stomach washes back up into the esophagus. You can take magnesium while on omeprazole if you manage the timing carefully—spacing doses at least two hours apart helps maintain effective absorption. Choosing highly bioavailable forms like citrate or glycinate also optimizes results. Plasma omeprazole concentrations are usually in a range of 0.2–1.2 mg/L in persons receiving the drug therapeutically by the oral route and 1–6 mg/L in people with acute overdose. Omeprazole can cause low magnesium levels, also known as hypomagnesemia, which can be serious. Decreased magnesium levels can cause seizures or heart rhythm problems. Omeprazole is a proton pump inhibitor that is used to treat symptoms of gastroesophageal reflux disease and other conditions caused by excess stomach acid. Omeprazole is used to treat certain stomach and esophagus problems (such as acid reflux, ulcers). It works by decreasing the amount of acid your stomach makes. It relieves symptoms such as heartburn, difficulty swallowing, and cough. PRILOSEC (omeprazole magnesium) for delayed-release oral suspension, 2.5 mg or 10 mg omeprazole, is supplied as a unit dose packet containing a fine yellow powder, consisting of white to brownish. What is this medication? OMEPRAZOLE (oh ME pray zol) is used to treat heartburn, stomach ulcers, reflux disease, or other conditions that cause too much stomach acid. It works by reducing the amount of acid in the stomach. It belongs to a group of medications called PPIs. Because there is a salt (magnesium) attached to the Omeprazole, it makes it easy to dissolve and can be taken on an empty stomach or with food. Whenever Omeprazole alone is taken, it should be taken prior to meals. PPIs work by reducing stomach acid production. While this helps with acid reflux and ulcers, adequate stomach acid is actually necessary for absorbing certain nutrients—including magnesium. Important: This isn't a drug interaction you can fix by separating doses.