OXYCONTIN will continue to release oxycodone and add to the oxycodone load for 24 to 48 hours or longer following ingestion, necessitating prolonged monitoring. OxyContin carries a Boxed Warning and contains oxycodone, a Schedule II controlled substance with an abuse potential similar to other Schedule II opioids. Oxycodone HCl Controlled-Release Tablets are an opioid agonist and a Schedule II controlled substance with an abuse liability similar to morphine. Oxycodone can be abused in a manner similar to other opioid agonists, legal or illicit. Oxycodone, sold under the brand names Roxicodone and OxyContin (which is the extended-release form) among others, is a semi-synthetic opioid used medically for the treatment of moderate to severe pain. The activity of OxyContin Tablets is primarily due to the parent drug oxycodone. OxyContin Tablets are designed to provide controlled delivery of oxycodone over 12 hours. Oxycodone acts on the central nervous system (CNS) to relieve pain. Oxycodone extended-release capsules or tablets should not be used if you need pain medicine for just a short time, such as when recovering from surgery. Oxycodone is used to manage pain severe enough to require an opioid pain medicine when other pain medicines do not treat pain well enough, or are not tolerated. Includes oxycodone side effects, dose, reviews, warnings, and more. Oxycontin (oxycodone hydrochloride) is used to treat moderate to severe pain. Learn side effects, dosage, drug interactions, warnings, patient labeling, reviews, and more. Get clear safety guidance for OxyCONTIN CR, including warnings, precautions, when to seek medical assistance, and how to use it correctly. Oxycodone is indicated for the management of moderate to severe pain where the use of an opioid analgesic is appropriate. Learn about common/serious side effects, dosages, drug interactions, and more.