Oxycodone is used to manage pain severe enough to require an opioid pain medicine when other pain medicines do not treat pain well enough, or are not tolerated. Includes oxycodone side effects, dose, reviews, warnings, and more. What is Oxycodone? Oxycodone is a semi-synthetic narcotic analgesic and historically has been a popular drug of abuse among the narcotic abusing population. Oxycodone, sold under the brand names Roxicodone and OxyContin (which is the extended-release form) among others, is a semi-synthetic opioid used medically for the treatment of moderate to severe pain. Oxycodone is an opioid medication that treats severe pain. It works by blocking pain signals in your brain. Why is this medication prescribed? Oxycodone is used to relieve severe pain. Oxycodone is in a class of medications called opiate (narcotic) analgesics. It works by changing the way the brain and nervous system respond to pain. Oxycodone is indicated for the management of moderate to severe pain where the use of an opioid analgesic is appropriate. Learn about common/serious side effects, dosages, drug interactions, and more. Overview: Oxycodone is a medicine that is used to help treat severe pain. Common side effects include constipation, nausea, vomiting, stomach pain, headache, and dizziness. Do not drive or do. Oxycodone is used to relieve pain severe enough to require opioid treatment and when other pain medicines did not work well enough or cannot be tolerated. It belongs to the group of medicines called opioid analgesics (pain medicines). Oxycodone is an opioid medication that takes on pain. It comes in tablet, capsule, or liquid form. Understand the uses, side effects, and precautions. NHS information about the medicine oxycodone, including what it's used for, who can take it, how to take it and side effects.