Medscape - Gastric ulcer, GERD, heartburn-specific dosing for Protonix (pantoprazole), frequency-based adverse effects, comprehensive interactions, contraindications, pregnancy & lactation. PROTONIX is indicated for maintenance of healing of erosive esophagitis and reduction in relapse rates of daytime and nighttime heartburn symptoms in adult patients with GERD. Controlled studies. This product information is intended only for residents of the United States. Protonix is a proton pump inhibitor that decreases the amount of acid produced in the stomach. Protonix is used to treat erosive esophagitis (damage to the esophagus from stomach acid caused by gastroesophageal reflux disease, or GERD) in adults and children who are at least 5 years old. Pantoprazole (Protonix) is a proton-pump inhibitor (PPI). It's used to treat symptoms of gastroesophageal reflux disease (GERD) in adults and children. It's also used to treat other conditions involving too much stomach acid, such as erosive esophagitis, in adults only. What is the most important information I should know about PROTONIX? You should take PROTONIX exactly as prescribed, at the lowest dose possible and for the shortest time needed. PROTONIX may help your acid-related symptoms, but you could still have serious stomach problems. Talk with your doctor. Protonix (Pantoprazole) may treat, side effects, dosage, drug interactions, warnings, patient labeling, reviews, and related medications including drug comparison and health resources. Find patient medical information for Pantoprazole (Protonix) on WebMD including its uses, side effects and safety, interactions, pictures, warnings, and user ratings Pantoprazole (Protonix) is a medication that treats conditions that cause too much stomach acid, like heartburn, stomach ulcers and reflux disease. Pantoprazole is used to treat certain conditions in which there is too much acid in the stomach. It is used to treat erosive esophagitis or heartburn caused by gastroesophageal reflux disease (GERD), a condition where the acid in the stomach washes back up into the esophagus.