Quetiapine is one of only two antipsychotics (the other is cariprazine) that produce equal efficacy as standalone therapies for mixed manic-depressive mood swings as they do in combination with an SSRI antidepressant. Quetiapine is used to treat schizophrenia in adults and children who are at least 13 years old. Medscape - Schizophrenia, bipolar disorder-specific dosing for Seroquel, Seroquel XR (quetiapine), frequency-based adverse effects, comprehensive interactions, contraindications, pregnancy &. SEROQUEL XR is a once-daily tablet approved in adults for add-on treatment to antidepressants for patients with major depressive disorder (MDD) who did not have an adequate response to antidepressant therapy; Find patient medical information for Quetiapine (Seroquel) on WebMD including its uses, side effects and safety, interactions, pictures, warnings, and user ratings Both formulations are effective treatment options with similar overall efficacy profiles, but the XR formulation offers the convenience of once-daily dosing which may significantly improve medication adherence in many patients. Quetiapine is used alone or together with other medicines to treat bipolar disorder (depressive and manic episodes) and schizophrenia. Quetiapine extended-release tablet is also used together with other antidepressants to treat major depressive disorder. Seroquel XR is a prescription medicine used to treat the symptoms of Schizophrenia and Bipolar Disorder, for maintenance, mania and depressive episodes and Major Depressive Disorder. Seroquel XR may be used alone or with other medications. Seroquel XR belongs to a class of drugs called Antipsychotics, 2nd Generation; Antimanic Agents. Seroquel XR is used to treat schizophrenia in adults and children who are at least 13 years old. Seroquel XR is used alone or in combination with divalproex or lithium to treat manic episodes in adults with bipolar disorder. The information provided on this site is intended for use by healthcare professionals practicing in the US. The dissemination of this information may be subject to different medical and regulatory requirements in other countries.