In most cases, you take tamoxifen once per day. Most doctors recommend taking tamoxifen at the same time each day. If you’ve been diagnosed with early-stage, hormone receptor-positive breast cancer, you take tamoxifen for at least five years after surgery to reduce the risk of recurrence. Find patient medical information for Tamoxifen on WebMD including its uses, side effects and safety, interactions, pictures, warnings, and user ratings Medscape - Breast cancer dosing for Soltamox (tamoxifen), frequency-based adverse effects, comprehensive interactions, contraindications, pregnancy & lactation schedules, and cost information. What is the dosage for tamoxifen (Soltamox)? The dose for metastatic breast cancer treatment, DCIS, and prevention of breast cancer is 10 mg twice daily or 20 mg once daily for 5 years. The dose for stimulation of ovulation is 5-40 mg twice daily for 4 days. Tamoxifen can be taken with food. The FDA-approved dosage for tamoxifen in breast cancer treatment is 20 mg daily, which can be given as a single dose or divided into two 10 mg doses (morning and evening) 1 The typical tamoxifen dosage for adults is 20 mg by mouth once daily. Some people may need a higher dosage of 40 mg daily, which is usually taken as 20 mg twice a day. You must take tamoxifen daily by mouth, preferably at the same time each day. The drug comes in two forms: Nolvadex® pill. Soltamox® liquid. How long should you take tamoxifen? Most people take tamoxifen or other hormone therapy for at least five years and sometimes, up to 10 years. Do not start, stop, or change the dosage of this medicine or any drug before seeking medical advice from your doctor, healthcare provider or pharmacist first. To do so may result in serious consequences or side effects. Tamoxifen blocks the actions of estrogen in breast tissue and is used to treat estrogen receptor-positive breast cancer in adults and to lower the risk of breast cancer in women with DCIS or at high risk. Learn about side effects, interactions, and indications. Detailed Tamoxifen dosage information for adults and children. Includes dosages for Breast Cancer, Breast Cancer - Adjuvant, Precocious Puberty and more; plus renal, liver and dialysis adjustments.