Ulcerative colitis is a type of inflammatory bowel disease that mainly affects the large intestine. Some treatments for ulcerative colitis include medications, diet changes, and sometimes surgery. Flare-ups can be triggered by stress, certain foods, or stopping medications. Ulcerative colitis (UC) is a chronic condition that happens when you have inflammation in your colon. Most people with UC experience periods of symptom flare-ups followed by periods of remission without symptoms. Signs and symptoms include diarrhea, bloody stools, abdominal cramping and weight loss Treatments include medication and surgery. Ulcerative colitis Diagnosis and testing To diagnose ulcerative colitis, healthcare professionals do a colonoscopy and collect tissue samples, called biopsies, from the lining of the colon. Other types of tests such as stool tests, MRI and CT scans can help rule out complications or other forms of inflammatory bowel disease, such as Crohn's. Find out about ulcerative colitis, a long-term (chronic) condition where the colon and rectum (large intestine or large bowel) become inflamed. Ulcerative colitis is a chronic inflammatory disease affecting the colon, and its incidence is rising worldwide. The pathogenesis is multifactorial, involving genetic predisposition, epithelial barrier defects, dysregulated immune responses, and. Ulcerative colitis (UC) is a type of inflammatory bowel disease that causes inflammation and ulcers in the lining of your large intestine. It typically begins in the rectum and spreads to the colon. Ulcerative colitis is an inflammatory bowel disease that causes chronic inflammation and ulcers in the superficial lining of the large intestine, also called the colon. Ulcerative colitis (UC) is one of the two types of inflammatory bowel disease (IBD), with the other type being Crohn's disease. [1] It is a long-term condition that results in inflammation and ulcers of the colon and rectum. [1][7] The primary symptoms of active disease are abdominal pain and diarrhea mixed with blood (hematochezia). [1] Weight loss, fever, and anemia may also occur. [1] Often. Ulcerative colitis (UC) is an inflammatory bowel disease that affects your large intestine, causing irritation, inflammation, and ulcers in the colon. Learn more about the symptoms, causes. Ulcerative colitis (UC) is the most common type of inflammatory bowel disease (IBD). It affects the inner lining of the colon and rectum, causing complete damage to the lining. People with UC often experience blood or mucous in their stool (poop) and feel an urgent need to empty their bowels. Complications can be serious, but most people with UC can control their symptoms and lead active lives.