WELLBUTRIN XL ® (bupropion hydrochloride) extended-release tablets is a prescription medicine used to treat adults with a certain type of depression called major depressive disorder, and for the prevention of autumn-winter seasonal depression (seasonal affective disorder). Bupropion is used to treat major depressive disorder (MDD) and to prevent seasonal affective disorder (SAD), which is sometimes called autumn-winter seasonal depression. It is also used as part of a support program to help people stop smoking. Bupropion is sold under different brand names. Medscape - Depression, smoking cessation-specific dosing for Wellbutrin XL, Aplenzin (bupropion), frequency-based adverse effects, comprehensive interactions, contraindications, pregnancy &. Wellbutrin XL (Bupropion Hydrochloride Extended-Release) may treat, side effects, dosage, drug interactions, warnings, patient labeling, reviews, and related medications including drug comparison and health resources. The FDA investigated these complaints and concluded that Budeprion XL is equivalent to Wellbutrin XL regarding bioavailability of bupropion and its main active metabolite hydroxybupropion. Find patient medical information for Bupropion (Wellbutrin, Zyban, and others) on WebMD including its uses, side effects and safety, interactions, pictures, warnings, and user ratings Wellbutrin XL: side effects, dosage, interactions, FAQs, reviews. Used for: depression, major depressive disorder, seasonal affective disorder Wellbutrin XL extended-release tablets, 150 mg of bupropion hydrochloride, are creamy-white to pale yellow, round tablets imprinted with “Wellbutrin XL 150” in black ink on one side and the other. For brand or generic Wellbutrin XL, the recommended starting dosage is 150 mg every morning. After 7 days, it may be increased to the target dosage of 300 mg per day. WELLBUTRIN (bupropion hydrochloride), an antidepressant of the aminoketone class, is chemically unrelated to tricyclic, tetracyclic, selective serotonin re-uptake inhibitor, or other known antidepressant agents.