The FDA investigated these complaints and concluded that Budeprion XL is equivalent to Wellbutrin XL regarding bioavailability of bupropion and its main active metabolite hydroxybupropion. Find patient medical information for Bupropion (Wellbutrin, Zyban, and others) on WebMD including its uses, side effects and safety, interactions, pictures, warnings, and user ratings The official site for WELLBUTRIN XL® provides information for healthcare professionals on clinical experience in Major Depressive Disorder (MDD) and Seasonal Affective Disorder (SAD). Understand the benefits of WELLBUTRIN XL®, its unique SmartCoat™ technology, and the differences between brand name and generic versions. Learn how to ensure you receive the brand name medication at the pharmacy. Wellbutrin (bupropion) is used to treat major depressive disorder and seasonal affective disorder. Includes Wellbutrin side effects, interactions and indications. Use in Smoking Cessation Treatment. WELLBUTRIN®, WELLBUTRIN SR®, and WELLBUTRIN XL are not approved for smoking cessation treatment, but bupropion under the name ZYBAN® is approved for this. Wellbutrin XL: side effects, dosage, interactions, FAQs, reviews. Used for: depression, major depressive disorder, seasonal affective disorder Wellbutrin XL (Bupropion Hydrochloride Extended-Release) may treat, side effects, dosage, drug interactions, warnings, patient labeling, reviews, and related medications including drug comparison and health resources. WELLBUTRIN XL prescription and dosage information for physicians and health care professionals. Pharmacology, adverse reactions, warnings, and WELLBUTRIN XLside effects. Bupropion is used to treat major depressive disorder (MDD) and to prevent seasonal affective disorder (SAD), which is sometimes called autumn-winter seasonal depression. It is also used as part of a support program to help people stop smoking. Bupropion is sold under different brand names.