Find patient medical information for Bupropion (Wellbutrin, Zyban, and others) on WebMD including its uses, side effects and safety, interactions, pictures, warnings, and user ratings Wellbutrin XL: side effects, dosage, interactions, FAQs, reviews. Used for: depression, major depressive disorder, seasonal affective disorder Wellbutrin XL ® (bupropion hydrochloride extended-release) tablets is indicated for the treatment of major depressive disorder (MDD), as defined by the Diagnostic and Statistical Manual (DSM). The official site for WELLBUTRIN XL® provides information for healthcare professionals on clinical experience in Major Depressive Disorder (MDD) and Seasonal Affective Disorder (SAD). Bupropion is used to treat major depressive disorder (MDD) and to prevent seasonal affective disorder (SAD), which is sometimes called autumn-winter seasonal depression. It is also used as part of a support program to help people stop smoking. Bupropion is sold under different brand names. Use in Smoking Cessation Treatment: WELLBUTRIN®, WELLBUTRIN SR®, and WELLBUTRIN XL are not approved for smoking cessation treatment, but bupropion under the name ZYBAN® is approved for this. Understand the benefits of WELLBUTRIN XL®, its unique SmartCoat™ technology, and the differences between brand name and generic versions. Learn how to ensure you receive the brand name medication at the pharmacy. What is Wellbutrin’s dosage? Here are details about the dosages of Wellbutrin sustained-release (SR) and extended-release (XL) oral tablets. Doctors prescribe Wellbutrin SR to treat MDD in. Wellbutrin XL and Wellbutrin SR are different formulations of the antidepressant bupropion. Both Wellbutrin XL and Wellbutrin SR may cause weight gain or weight loss, but weight loss is more common. Wellbutrin XL (Bupropion Hydrochloride Extended-Release) may treat, side effects, dosage, drug interactions, warnings, patient labeling, reviews, and related medications including drug comparison and health resources.