In general, generic drugs tend to cost less than brand-name drugs. The cost of levothyroxine without insurance is likely higher than the cost with insurance. However, if you don’t have. View SYNTHROID® cost and insurance coverage information, including SYNTHROID® co-pay card and Synthroid® Delivers Program. You have to pay? That’s awful. In the U.K. prescriptions cost under £10 regardless of the medication but for thyroid medication, you’re exempt from paying that. Even then, because you’re diagnosed with hypothyroidism, all prescriptions become free, even medication that’s unrelated to hypothyroidism. Your cost for Synthroid may vary, depending on the specific dose your doctor prescribes. Your pharmacist can give you the price of Synthroid based on your specific prescription. We discovered that brand name Synthroid is substantially less expensive if you purchase it from Canada. A three-month supply costs between $25 and $60, less than a 30-day bottle from the U.S. In some cases, Synthroid can be at least two or three times more expensive than the generic version. In some people, the two versions are not entirely interchangeable. Synthroid costs more than you’d expect for an old drug. Here’s what keeps the price high and what it means for your thyroid medication costs. Compare prices and print coupons for Synthroid and other drugs at CVS, Walgreens, and other pharmacies. Prices start at $165.25. Costs for Synthroid, a brand-name thyroid medication, can be high for many reasons, including its patent and your insurance coverage level. Generic versions may become available after the patent expires, making the drug more affordable overall. Your cost may depend on your treatment plan, your insurance coverage (if you have it), and the pharmacy you use. To find out how much you’ll pay for Synthroid, including what your out-of-pocket.