Learn about tizanidine (Zanaflex) usage and dosing. Read the latest news and reviews about the drug as well as potential side effects and popular alternatives. Tizanidine is a short-acting muscle relaxer. It works by blocking nerve impulses (pain sensations) that are sent to your brain. Tizanidine is used to treat spasticity by temporarily relaxing muscle tone. Tizanidine may also be used for purposes not listed in this medication guide. Find patient medical information for Tizanidine (Zanaflex) on WebMD including its uses, side effects and safety, interactions, pictures, warnings, and user ratings Zanaflex (Tizanidine) may treat, side effects, dosage, drug interactions, warnings, patient labeling, reviews, and related medications including drug comparison and health resources. Tizanidine is used to help relax certain muscles in your body. It relieves spasms, cramping, and tightness of the muscles caused by medical problems, including multiple sclerosis or certain injuries to the spine. Learn about Zanaflex: What is it used for, what you need to know before taking, important warnings and safety info, how to take, side effects and more. Zanaflex is a central alpha-2-adrenergic agonist indicated for the management of spasticity. Because of the short duration of therapeutic effect, treatment with Zanaflex should be reserved for those daily activities and times when relief of spasticity is most important. ( 1) Tizanidine, sold under the brand name Zanaflex among others, is an alpha-2 (α 2) adrenergic receptor agonist, [2] similar to clonidine, that is used to treat muscle spasticity due to spinal cord injury, multiple sclerosis, and spastic cerebral palsy. [3] Zanaflex (tizanidine) is a short-acting muscle relaxer used to treat spasticity by temporarily relaxing muscle tone. Includes Zanaflex side effects, interactions and indications. Tizanidine (Zanaflex) is a muscle relaxant that treats muscle spasms. It relaxes your muscles, which reduces muscle stiffness.