Zanaflex (tizanidine) is a short-acting muscle relaxer used to treat spasticity by temporarily relaxing muscle tone. Includes Zanaflex side effects, interactions and indications. Tizanidine (Zanaflex) is a muscle relaxant that treats muscle spasms. It relaxes your muscles, which reduces muscle stiffness. Description Tizanidine is used to help relax certain muscles in your body. It relieves spasms, cramping, and tightness of the muscles caused by medical problems, including multiple sclerosis or certain injuries to the spine. Tizanidine does not cure these problems, but it may allow other treatment, such as physical therapy, to be more helpful in improving your condition. Tizanidine acts on the. Tizanidine, sold under the brand names Zanaflex and Sirdalud among others, is an α 2 -adrenergic receptor agonist and muscle relaxant which is used to treat muscle spasticity due to spinal cord injury, multiple sclerosis, and spastic cerebral palsy. [1][3][4] Its effectiveness appears to be similar to that of other muscle relaxants like baclofen or diazepam. [5] The drug is taken orally. [6. Learn about tizanidine (Zanaflex) usage and dosing. Read the latest news and reviews about the drug as well as potential side effects and popular alternatives. Zanaflex (Tizanidine) may treat, side effects, dosage, drug interactions, warnings, patient labeling, reviews, and related medications including drug comparison and health resources. Find patient medical information for Tizanidine (Zanaflex) on WebMD including its uses, side effects and safety, interactions, pictures, warnings, and user ratings Zanaflex is known to be substantially excreted by the kidney, and the risk of adverse reactions to this drug may be greater in patients with impaired renal function. Learn about Zanaflex: What is it used for, what you need to know before taking, important warnings and safety info, how to take, side effects and more. Tizanidine is a short-acting muscle relaxant and is used to treat spasticity. Learn about side effects, interactions and indications.