Learn how often to take pantoprazole, the best time of day, and how long it’s safe to use based on your condition. Pantoprazole (Protonix) is a medication that treats conditions that cause too much stomach acid, like heartburn, stomach ulcers and reflux disease. Pantoprazole is a proton-pump inhibitor (PPI) and its effectiveness is similar to that of other PPIs. [10] It is available by mouth and by injection into a vein. Find patient medical information for Pantoprazole (Protonix) on WebMD including its uses, side effects and safety, interactions, pictures, warnings, and user ratings Pantoprazole (Protonix) is a proton-pump inhibitor (PPI). It's used to treat symptoms of gastroesophageal reflux disease (GERD) in adults and children. It's also used to treat other conditions involving too much stomach acid, such as erosive esophagitis, in adults only. Pantoprazole oral tablet is used to reduce the amount of stomach acid your body makes. It helps treat painful symptoms caused by conditions such as gastroesophageal reflux disease (GERD). Pantoprazole is used to treat damage from gastroesophageal reflux disease (GERD), a condition in which backward flow of acid from the stomach causes heartburn and possible injury of the esophagus (the tube between the throat and stomach) in adults and children 5 years of age and older. Pantoprazole is used to treat certain conditions in which there is too much acid in the stomach. It is used to treat erosive esophagitis or heartburn caused by gastroesophageal reflux disease (GERD), a condition where the acid in the stomach washes back up into the esophagus. Learn about the side effects of pantoprazole, from common to rare, for consumers and healthcare professionals. Pantoprazole is a proton pump inhibitor that decreases the amount of acid produced in the stomach. Pantoprazole is used to treat erosive esophagitis (damage to the esophagus from stomach acid caused by gastroesophageal reflux disease, or GERD) in adults and children who are at least 5 years old.