Evidence-based summary of the 2025 ACG updated guidelines for ulcerative colitis. How can healthcare providers manage ulcerative colitis (UC) in adults? What are appropriate therapies for mild-to-moderate disease, moderate-to severe disease and the hospitalized patient? Ulcerative colitis (UC) is one of the two types of inflammatory bowel disease (IBD), with the other type being Crohn's disease. [1] It is a long-term condition that results in inflammation and ulcers of the colon and rectum. [1][7] The primary symptoms of active disease are abdominal pain and diarrhea mixed with blood (hematochezia). [1] Ulcerative colitis is an inflammatory bowel disease that causes chronic inflammation and ulcers in the superficial lining of the large intestine, also called the colon. Ulcerative colitis types are classified by how much of the colon is affected. Learn the symptoms, severity, and differences between proctitis, left-sided colitis, pancolitis, and more. Ulcerative colitis (UC) is an inflammatory bowel disease. It causes irritation, inflammation, and ulcers in the lining of your large intestine (also called your colon). Ulcerative colitis (UC) is the most common type of inflammatory bowel disease (IBD). It affects the inner lining of the colon and rectum, causing complete damage to the lining. People with UC often experience blood or mucous in their stool (poop) and feel an urgent need to empty their bowels. Ulcerative colitis (UC) is a type of inflammatory bowel disease that causes inflammation and ulcers in the lining of your large intestine. It typically begins in the rectum and spreads to the. Ulcerative colitis (UC) is a lifelong condition that causes inflammation and ulcers inside your colon (large intestine). UC is one of the most common types of inflammatory bowel disease (IBD), alongside Crohn’s disease. Ulcerative colitis (UC) is an inflammatory bowel disease affecting the colon and rectum, causing significant digestive distress. While there is no cure, treatments like medications and lifestyle changes can help manage the symptoms. Medicines cannot cure ulcerative colitis, but they can control symptoms, reduce inflammation and help people stay in remission for long periods. The only true cure is surgery to remove the colon and rectum.